Boris Johnson is under pressure from scores of Conservative MPs to detail a “road-map out of lockdown” as more people in England come under the toughest coronavirus restrictions.

The Prime Minister has been warned by a group of 50 Tory backbenchers representing northern constituencies that the pandemic is threatening his election pledge to “level-up” the country.

Meanwhile, Covid-19 is spreading across London with more than 13,000 cases in a week , according to official figures. They also show that six of the ten boroughs with the highest coronavirus rates are now in west London.

It comes as the national death toll rose by 367 overnight – the highest daily jump since May 27 – as another 22,885 cases of the disease were recorded.

In other developments, a study has revealed that protective antibodies have declined among the general population since mid-July. Research by Imperial College London estimated just 4.4 per cent of adults had some form of immunity against Covid-19 in September, compared with six per cent between June 20 and July 13.

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